What is Psoriatic Arthritis:
Psoriatic arthritis is a type of arthritis that affects the person suffering from psoriasis. Psoriasis, a condition in which skin has the red patches along with silvery scales on it.
It is generally called arthritis psoriatica, arthropathies psoriasis and is a type of inflammatory arthritis causing intensive inflammation at the joints.
The major symptoms of this arthritis are swelling in joints, inflammation in joints, red and itchy skin. The major risk factor of this disease is family history, age, and psoriasis. The treatment of psoriatic arthritis does not exist thus the main focus is to control the symptoms and reduce the inflammation.
Does psoriatic arthritis affect other organs:
There are 78 major joints in the body and psoriatic arthritis can affect any one of these, although some joints are more likely to be affected than others.
Psoriatic arthritis usually doesn’t affect major organs such as the lungs or liver. Apart from this, patients may be more likely to develop a painful red eye. If this affects you, it’s important not to ignore it. These mentioned signs and symptoms can be caused by a condition named uveitis, also addressed as iritis, which is inflammation at the front of the eye. This can damage your eyesight if untreated.
Discuss this with your doctor who should help you recognise these symptoms, and explain what you should do if it occurs.
People with psoriasis and psoriatic arthritis may have a little bit greater risk than other people of developing heart disease, so it’s quite necessary to address anything that can add to this risk, such as smoking, high alcohol intake, being overweight or blood pressure problems.
In order to control the procedure of psoriatic arthritis via drugs are:
Non- steroidal anti-inflammatory drugs
Disease modifying antirheumatic drugs
Biological response modifiers
Phosphodiesterase-4 inhibitors
Surgery is also a successful treatment of psoriatic arthritis by the replacement of joints.
There is apremilast medication which is a quite effective treatment and also most recommended amongst the doctor.
Apremilast 30 mg tablets: Is a drug that is used in the treatment of psoriatic arthritis. It is sold under the brand name of Otezla and thus this can commonly be termed as Otezla tablets. Apremilast is an active pharmaceutical ingredient of Otezla, which is available in various concentrations such as 10mg, 20mg and 30 mg.
Apremilast 30mg tablet is a selective inhibitor of phosphodiesterase-4 enzyme. This PDE-4 enzyme blocks the production of TNF-alpha from human rheumatoid synovial cells. Apremilast or Otezla do not cure psoriatic arthritis rather it only reduces the pain, swelling and inflammation in the joints.
Apremilast 30mg tablets must be avoided by pregnant women or must be taken with doctor's advice. Otezla is taken orally with water. The price of Otezla 30mg is very economical and is available at registered pharmaceutical companies.
The major side effects of Apremilast tablets (Otezla 30mg) are as:
Vomiting
Diarrhea
Loss of appetite
Weight loss
Psychological disorder
Depression
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