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A Brief On Side Effects of Pomalidomide



Pomalidomide is used in order to treat adults with multiple myeloma. This is a sort of cancer of plasma cells (a type of white blood cell (WBC) found in the bone marrow).

This drug is either used with the dexamethasone and bortezomib for patients who:

  • had their disease worsen on their last treatment

  • have already had at least one prior treatment regimen including lenalidomide

Or dexamethasone for patients whose disease has gotten worse after at least two other treatments including lenalidomide and bortezomib.


Pomalidomide works in the bone marrow. It stimulates the immune system to attack the growth of cancerous myeloma cells. It helps in resisting the growth of the cancer cells. Pomalidomide when used with the dexamethasone or bortezomib can stop or prevent multiple myeloma from getting worse.


Do not take this medication if:

  • You are pregnant

  • You are at risk of becoming pregnant

  • You become pregnant during pomalidomide treatment

  • You are breastfeeding

  • You are allergic to pomalidomide, lenalidomide or thalidomide or any of the other ingredients in pomalyst.

Side Effects of Pomalidomide: Like all medicines, pomalidomide for multiple myeloma can have side effects. These are not all the possible side effects that may be experienced when taking Pomalidomide 4mg. If any side effects not listed here are experienced, or these bother you or do not go away, tell your healthcare professional.

Side effects may include:

  • Headache

  • Tremor

  • Difficulty sleeping

  • Tiredness

  • Rash

  • Itching

  • Fever

  • Flu (influenza), nose, throat and sinus infections

  • Swelling of arms or legs

  • Changes in taste (dysgeusia)

  • Inflammation of mouth and lips (stomatitis)

  • Diarrhea

  • Nausea

  • Constipation

  • Vomiting

  • Loss of appetite

  • Indigestion (dyspepsia)

  • Bloating (abdominal distension)

  • Weight loss

  • Abdominal pain

  • Pelvic pain

  • Back pain

  • Chest pain

  • Muscle spasm

  • Falls

  • Difficulty breathing

  • Breathlessness (dyspnea)

  • Cough

  • Dizziness

Pomalidomide 2 mg can be responsible for causing abnormal blood test results. Your healthcare providers will determine when to perform blood tests and will interpret the results.

This is not a complete list of adverse effects. If you have any unexpected adverse effects after taking this multiple myeloma medication, please discuss with your doctor or pharmacist.

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